This Lower East Side award-winner from pioneering pizzaiolo Anthony Mangieri was named the number-one pizzeria in the world by 50 Top Pizza in 2022 and 2024. Unsurprisingly, the pies—simple and classic on naturally leavened dough—are the stars at the bustling, elbow-to-elbow space. But don't miss the house-made gelato and fresh-fruit sorbetti, nor the standout wines from Campania.